Prostate cancer may be asymptomatic at the early stage and often has an indolent course, and may require minimal or even no treatment. Although 2,293,818 new cases are estimated until 2040, a small variation in mortality will be observed (an increase of 1.05%).
Reasons for this disparity have been hypothesized to differences in social, environmental and genetic factors. Of note, for African-American men, the incidence rates are higher when compared to the White men, with 158.3 new cases diagnosed per 100,000 men and their mortality is approximately twice as White men. The incidence and mortality of prostate cancer worldwide correlate with increasing age with the average age at the time of diagnosis being 66 years. Prostate cancer is the second most frequent malignancy (after lung cancer) in men worldwide, counting 1,276,106 new cases and causing 358,989 deaths (3.8% of all deaths caused by cancer in men) in 2018. Up-to-date statistics on prostate cancer occurrence and outcomes along with a better understanding of the etiology and causative risk factors are essential for the primary prevention of this disease. Screening is highly recommended at age 45 for men with familial history and African-American men. There is no evidence yet on how to prevent prostate cancer however, it is possible to lower the risk by limiting high-fat foods, increasing the intake of vegetables and fruits and performing more exercise. African-American men have the highest incidence rates and more aggressive type of prostate cancer compared to White men. Prostate cancer incidence and mortality rates are strongly related to the age with the highest incidence being seen in elderly men (> 65 years of age). Differences in the incidence rates worldwide reflect differences in the use of diagnostic testing. Based on GLOBOCAN 2018 estimates, 1,276,106 new cases of prostate cancer were reported worldwide in 2018, with higher prevalence in the developed countries. Prostate cancer may be asymptomatic at the early stage and often has an indolent course that may require only active surveillance. Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth leading cause of death worldwide.
0 kommentar(er)
